ISSN 1662-4009 (online)

ey0017.4-9 | New perspectives | ESPEYB17

4.9. Growth hormone deficiency and excess alter the gut microbiome in adult male mice

EA Jensen , JA Young , Z Jackson , J Busken , EO List , RK Carroll , JJ Kopchick , ER Murphy , DE Berryman

To read the full abstract: Endocrinology, April 2020, 161(4):1–18The aim of this study was to examine the role of growth hormone (GH) on gut microbiome and intestinal phenotype by using two animal models characterized by an opposite GH status: GH gene-disrupted (GH-/-) mice, characterized by GH deficiency; and bovine GH transgenic (bGH) mice with chronic GH excess. The abundance of common bacterial genera, such as Parasutterella, Ruminococc...